Package: WSSmod
Title: Weighted Sum Scores for Protein Network Modules
Version: 0.1.0.9000
Authors@R: c(
    person("Robert", "Butler", , "rrbutler@stanford.edu", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0003-0200-8682")),
    person("WSSmod authors", role = "cph")
  )
Description: Computes Weighted Sum Score (WSS) module-level summaries
        from proteomic data. Protein-level values are sign-aligned to
        their association with core biomarkers and combined within
        'STRING' network modules, weighted by network connectivity and
        association strength. Bundled reference modules and a fitted
        'joinet' model also allow all module scores to be predicted
        from age, sex and a small panel of plasma biomarkers, without
        measuring the full proteomic panel. The method is described in
        Butler et al. (2026) <doi:10.64898/2026.08.14.26360394>.
License: MIT + file LICENSE
Encoding: UTF-8
Language: en-US
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Depends: R (>= 3.5.0)
Imports: data.table
Suggests: glmnet, joinet, knitr, rmarkdown, RNOmni, testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
LazyData: true
URL: https://github.com/Longo-Lab/WSSmod,
        https://Longo-Lab.github.io/WSSmod/
BugReports: https://github.com/Longo-Lab/WSSmod/issues
Repository: https://longo-lab.r-universe.dev
Date/Publication: 2026-11-04 20:25:50 UTC
RemoteUrl: https://github.com/longo-lab/wssmod
RemoteRef: HEAD
RemoteSha: 6bc22b73a58882dc333a1ce2aceac2e79265117f
NeedsCompilation: no
Packaged: 2026-11-04 22:09:06 UTC; root
Author: Robert Butler [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0200-8682>),
  WSSmod authors [cph]
Maintainer: Robert Butler <rrbutler@stanford.edu>