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# CITATION.cff file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "WSSmod" in publications use:'
type: software
license: MIT
title: 'WSSmod: Weighted Sum Scores for Protein Network Modules'
version: 0.1.0.9000
doi: 10.64898/2026.08.14.26360394
identifiers:
- type: doi
  value: 10.32614/CRAN.package.WSSmod
abstract: Computes Weighted Sum Score (WSS) module-level summaries from proteomic
  data. Protein-level values are sign-aligned to their association with core biomarkers
  and combined within 'STRING' network modules, weighted by network connectivity and
  association strength. Bundled reference modules and a fitted 'joinet' model also
  allow all module scores to be predicted from age, sex and a small panel of plasma
  biomarkers, without measuring the full proteomic panel. The method is described
  in Butler et al. (2026) <https://doi.org/10.64898/2026.08.14.26360394>.
authors:
- family-names: Butler
  given-names: Robert
  email: rrbutler@stanford.edu
  orcid: https://orcid.org/0000-0003-0200-8682
preferred-citation:
  type: article
  title: Alzheimer's disease blood biomarkers reveal proteomic modules of disease
    progression
  authors:
  - family-names: Butler
    given-names: Robert R.
  - family-names: Brown
    given-names: Michael P.
  - family-names: Weber
    given-names: Audrey
  - family-names: Cary
    given-names: Greg A.
  - family-names: Le Guen
    given-names: Yann
  - family-names: Moran Losada
    given-names: Patricia
  - family-names: Mendiola
    given-names: Justin H.
  - family-names: Henderson
    given-names: Victor W.
  - family-names: Sha
    given-names: Sharon J.
  - family-names: Poston
    given-names: Kathleen L.
  - family-names: Andreasson
    given-names: Katrin I.
  - family-names: Wagner
    given-names: Anthony D.
  - family-names: Mormino
    given-names: Elizabeth C.
  - family-names: Wyss-Coray
    given-names: Tony
  - family-names: Longo
    given-names: Frank M.
  - family-names: Wilson
    given-names: Edward N.
  journal: medRxiv
  year: '2026'
  doi: 10.64898/2026.08.14.26360394
  url: https://www.medrxiv.org/content/10.64898/2026.08.14.26360394v1.full-text
  notes: Preprint
repository: https://longo-lab.r-universe.dev
repository-code: https://github.com/Longo-Lab/WSSmod
commit: 6bc22b73a58882dc333a1ce2aceac2e79265117f
url: https://Longo-Lab.github.io/WSSmod/
date-released: '2026-11-04'
contact:
- family-names: Butler
  given-names: Robert
  email: rrbutler@stanford.edu
  orcid: https://orcid.org/0000-0003-0200-8682